NTA follows single particles movement into a solution and calculate their hydrodynamic diameter based on Brownian motion equations. Its advantage are its association with concentration information to provide distribution per volume, and its simplicity once the instrument is available. However, optical limitation reduces its sensitivity to vesicles bigger than 50-70 nm in scatter mode. Fluorescent staining may help to detect smaller particles.
EVerZom offers NTA measurements of any kind of samples using the ZetaView® QUATT (Particle Metrix, Germany) or the NS300 (Malvern, UK) with the cheapest price compared to other analysis.